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Phenylketonuria (PKU), also called Folling's disease, is an inherited disorder that occurs when patients are missing an enzyme that is needed to process a protein called phenylalanine.

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The early chapters, which describe the Jesuit missionaries who brought the bark of the cinchona tree to the Old World, gave the cynic in me a greater appreciation for the fact that there were individuals within the Church who did great work in service of humanity.

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The insertion of saponins into biomembrane structure affects its fluidity and function with resultant introduction of holes and pores, which elicits leaky cells and eventually cells death.

We searched The Cochrane Neuromuscular Disease Group Register, The Cochrane Central Register of Controlled Trials (CENTRAL) (Issue 3, 2010), MEDLINE, EMBASE and reference lists of articles up to July 2010.

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Chill Tonic may not have been exactly tasteless, but in 1878 he suspended quinine in liquid form.

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In symptomatic patients, antibiotic and antimalarial therapy should be started immediately after diagnosis to reduce the level of parasitemia.

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Drenching night sweats, acute dizziness (taking meclizine for that, seems to help but might be exacerbating next symptom) marked tiredness by afternoon (take my dose in the morning; maybe I should switch to evening), two infections in two months including pneumonia, ringing in the ears.

When quinine treatment is terminated, however, many recovered patients experience another attack of malaria several weeks later.

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Call your doctor at once if you have a weak pulse, if you faint or collapse, if you have fever, confusion, pale or yellowed skin, dark colored urine, hearing or vision loss, purple spots under your skin, a blistering or peeling skin rash, or if you urinate less than usual or not at all.

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Quinine consumed for the treatment of leg cramps should be prescribed and monitored by physicians, and people who consume quinine in commercial beverages must be warned of the health risks.

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Glycobiology has revealed that the glycosidic residue is crucial for bioactivity; in other circumstances, glycosylation improves pharmacokinetic parameters and may serve as leads to the development of new and more active drugs, as typified by the recently developed antibiotics-vancomycin ().

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See full prescribing information for quinine sulfate capsules, USP.

Quinine has been used by the Quechua of South America for medicinal purposes for centuries, and has been researched since the 1930s and 1940s as a cure for muscle cramps.

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Serum electrolytes, ketones, blood glucose and if indicated, blood pH, lactate levels, and even blood metformin levels may be useful.

Barnes KI, Durrheim DN, Little F, Jackson A, Mehta U, Allen E, Dlamini SS, Tsoka J, Bredenkamp B, Mthembu DJ, White NJ, Sharp BL: Effect of artemether-lumefantrine policy and improved vector control on malaria burden in KwaZulu-Natal, South Africa.

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The most important new class of antimalarial agents is the artemisinins, which are natural products developed in China beginning in the 1960s.

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At the end of each week of the first four weeks of the trial, these patients had their dosages of Metformin hydrochloride tablets increased by 500 mg if they had failed to reach target fasting plasma glucose.

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An injury to the spinal cord could lead to the intestines being more sluggish, as well as decreased physical activity, fluid intake, and dietary fiber.

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Much as Robert Koch had seen in Africa, Neiva encountered infected children whose only pathological manifestation of the disease was a dilated spleen.

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More than 7000 severely ill patients have now been included in randomised comparisons of parenteral artesunate and quinine ().

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