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ISEL did not meet its primary objective of a statistically significant improvement in OS for IRESSA compared to placebo, but did confirm a number of important clinical benefits for IRESSA including tumour shrinkage and a significant improvement in time to treatment failure.
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There is a separate application form for each drug, which includes information about the cancer type, stage and any other conditions that have to be met, such as other treatments you must have already had.
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Craniopharyngiomas do NOT represent cancers, and craniopharyngioma does not spread to other parts of the central nervous system or body; however, craniopharyngiomas develop in a part of the brain where their growth can cause problems with hormone secretion (from compression of the pituitary gland), or vision (from compression of the nerves responsible for sight).
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Similar results were observed in other breast cancer cell lines (luminal B type MCF7 and triple negative SUM159 cells).
Neoadjuvant is therapy given before the primary therapy to improve effectiveness (e.
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The team used an approach called whole-exome sequencing to identify these mutations.
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This mass was sufficiently large to cause superior vena cava syndrome, a syndrome resulting from a blockage of venous return to the heart from the upper half of the body.
And if he comes off of it, his cancer will return within 6 weeks.
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Disclosure: No potential conflicts of interest were reported by the authors, planners, reviewers, or staff managers of this article.
The results of a large phase II, multicenter, randomized discontinuation trial published by Ratain et al.
Also, paclitaxel is exported from the p-glycoprotein and other ATP-binding cassette transporters placed at the luminal membrane of brain capillaries, as an explanation for the low concentrations of taxanes in the CNS.
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